Brain morphometry correlates of pharmacoresistancy in schizophrenia
نویسندگان
چکیده
M. Quarantelli, O. Palladino, A. Prinster, V. Schiavone, B. Carotenuto, A. Brunetti, G. Ventrella, A. Marsili, A. De Bartolomeis, and M. Salvatore Biostructure and Bioimaging Institute, National Research Council, Naples, Italy, Institute of Psychiatry, University “Federico II”, Naples, Italy, 3 “S.D.N.” Foundation, Naples, Italy, Department of Biomorphological and Functional Sciences, University “Federico II”, Naples, Italy
منابع مشابه
Neural correlates of cognitive impairment in schizophrenia.
BACKGROUND Cognitive impairment is an established feature of schizophrenia. However, little is known about its relationship to the structural and functional brain abnormalities that characterise the disorder. Aims To identify structural and/or functional brain abnormalities associated with schizophrenic cognitive impairment. METHOD We carried out structural magnetic resonance imaging (MRI) an...
متن کاملVoxel-based gray and white matter morphometry correlates of hallucinations in schizophrenia: The superior temporal gyrus does not stand alone☆☆☆
INTRODUCTION Auditory verbal hallucinations (AVH) in schizophrenia (SZ) have been proposed to result from abnormal local, interregional and interhemispheric integration of brain signals in regions involved in language production and perception. This abnormal functional integration may find its base in morphological abnormalities. Structurally, AVHs have been frequently linked to abnormal morpho...
متن کاملStructural Alterations of the Social Brain: A Comparison between Schizophrenia and Autism
Autism spectrum disorder and schizophrenia share a substantial number of etiologic and phenotypic characteristics. Still, no direct comparison of both disorders has been performed to identify differences and commonalities in brain structure. In this voxel based morphometry study, 34 patients with autism spectrum disorder, 21 patients with schizophrenia and 26 typically developed control subject...
متن کاملDuration of illness, regional brain morphology and neurocognitive correlates in schizophrenia.
INTRODUCTION Previous studies examining brain effects of duration of illness in schizophrenia have focused on either cortical or subcortical structures. Hence this study sought to elucidate the regional grey matter changes (both cortical and subcortical) and neurocognitive correlates with increased duration of illness in a large sample of patients with schizophrenia using voxel-based morphometr...
متن کاملDecreased Left Putamen and Thalamus Volume Correlates with Delusions in First-Episode Schizophrenia Patients
Background Delusional thinking is one of the hallmark symptoms of schizophrenia. However, the underlying neural substrate for delusions in schizophrenia remains unknown. In an attempt to further our understanding of the neural basis of delusions, we explored gray matter deficits and their clinical associations in first-episode schizophrenia patients with and without delusions. Methods Twenty-...
متن کامل